Postdoctoral Research Scientist Pharmacokinetics/Pharmacodynamics modeling and simulation (m/f), Sophia

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At Bayer you have the opportunity to be part of a culture where we value the passion of our employees to innovate and give them the power to change.

Missions

Give scientific support on topics within area of expertise & Participate and support interdisciplinary research projects.

• Develop physiologically-based kinetic/dynamic (PBK/D) models to characterize the dose-response curves in several organs of interest within the context of adverse outcome pathways (AOPs) in mammals
• Refine the model in close collaboration with study directors and project team members by providing input for several experimental aspects such as :in vitro and/or in vivo study designs, safety endpoints, required model parameters, and timepoints measurements
• Investigate interspecies differences
• Derive quantitative in vitro-to-in vivo extrapolations (qIVIVE)
• Collaborate and interact with an international interdisciplinary project team
• Review appropriate literature pertaining to research project
• Present and communicate study findings, results, analyses, and future direction to project partners
• Collaborate in the preparation of materials for presentation and publications

Profile

• MSc, PhD, PharmD, or equivalent in pharmacometrics, pharmaceutical sciences, mathematics, or another relevant Life Science discipline.
• Strong expertise in modeling and simulation : physiologically-based kinetic/dynamic (PBK/D) modeling required, and mechanistic TK/TD modeling would be a plus
• Broad understanding of physiology, biology, toxicology, and statistics.
• Proficiency with PK-Sim® and R required, experience with other M&S software would be a plus.
• Fluent in English (written and oral).
• Excellent communication and negotiation skills; influencing and problem solving
• Ability to work in teams across multiple regions (cultural awareness) and to work autonomously.