Molecular Designer (F/H/D), Lyon

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At Bayer you have the opportunity to be part of a culture where we value the passion of our employees to innovate and give them the power to change.

Mission

• Molecular Design & Digital Innovation
• Design, propose, and optimize new small molecules with fungicidal, insecticidal, or herbicidal potential.
• Perform hit triage, clustering, and prioritization from diverse hit‑finding approaches (e.g. HTS, fragment screening, DEL, virtual or structure‑based screening).
• Apply structure‑based, target‑based, and data‑driven design approaches to guide early discovery projects.
• Integrate digital tools such as cheminformatics, molecular modeling, and machine learning to support hit identification and multi‑parameter optimization.
• Translate SAR, biological, and physicochemical data into clear design hypotheses and recommendations.
• Contribute to compound pool rejuvenation and targeted library design initiatives.
• Organic Synthesis & Laboratory Coordination
• Design and execute efficient, safe, and robust synthetic routes for new and diverse molecules.
• Coordinate internal and/or external chemistry resources to deliver key project compounds.
• Ensure high‑quality experimental documentation and contribute to intellectual property generation.
• Maintain high standards of laboratory safety, regulatory compliance, and risk assessment.
• Collaboration, Site & Hub Contribution
• Work closely with biology, screening, computational chemistry, and regulatory colleagues in multidisciplinary project teams.
• Collaborate with colleagues across the research center and global R&D hubs.
• Contribute to chemistry digitalization, knowledge sharing, mentoring, and continuous improvement initiatives at site and hub level.
• Support site and hub activities that strengthen scientific collaboration, operational excellence, and safety culture.

Profile

• PhD in Organic Chemistry, Medicinal Chemistry, or a related scientific field.
• Strong expertise in organic synthesis and modern analytical techniques (e.g. NMR, LC‑MS, HPLC).
• Solid understanding of molecular design, SAR, and early discovery workflows.
• Experience with, or strong interest in, digital and data‑driven approaches applied to chemistry.
• Team‑oriented, scientifically curious, and comfortable working in multidisciplinary environments.
• Fluent in English and French; German is an advantage.